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Message: <blockquote data-quote="imhotep" data-source="post: 31344556" data-attributes="member: 562115">Yes.. there is the Blood-Brain Barrier (BBB), but there are many pathogens that can cross it.  Briefly these use three mecahnisms - Transcellular, Paracellular and the Trojan Horse mechanism. The therapeutic drugs use the Trojan Horse approach where the drug is fused with a molecule that's able to pass the blood–brain barrier via a transporter protein.Also note that the brain is protected by the immune system and also regulates the immune system for the rest of the body too.</blockquote>

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