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<blockquote data-quote="pdnaclk" data-source="post: 11744937" data-attributes="member: 358615"><p><strong><span style="color: #0062A3">[FONT=&quot]CLINDAMYCIN[/FONT]</span></strong></p><p> <span style="color: #0062A3">[FONT=&quot]Indications [/FONT]</span><span style="color: #2B2622">[FONT=&quot]see notes above; staphylococcal bone and[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]joint infections, peritonitis; falciparum malaria (section[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]5.4.1)[/FONT]</span></p><p> <span style="color: #0062A3">[FONT=&quot]Cautions [/FONT]</span><span style="color: #2B2622">[FONT=&quot]discontinue immediately if diarrhoea or colitis[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]develops; monitor liver and renal function if[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]treatment exceeds 10 days, and in neonates and[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]infants; avoid rapid intravenous administration; avoid[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]in acute porphyria (section 9.8.2); [/FONT]</span><span style="color: #2B2622">[FONT=&quot]interactions:[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]Appendix 1 (clindamycin)[/FONT]</span></p><p> <span style="color: #0062A3">[FONT=&quot]Contra-indications [/FONT]</span><span style="color: #2B2622">[FONT=&quot]diarrhoeal states; avoid injections[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]containing benzyl alcohol in neonates (see under[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]preparations below)[/FONT]</span></p><p> <span style="color: #0062A3">[FONT=&quot]Pregnancy [/FONT]</span><span style="color: #2B2622">[FONT=&quot]not known to be harmful[/FONT]</span></p><p> <span style="color: #0062A3">[FONT=&quot]Breast-feeding [/FONT]</span><span style="color: #2B2622">[FONT=&quot]amount probably too small to be[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]harmful but bloody diarrhoea reported in 1 infant[/FONT]</span></p><p> <span style="color: #0062A3">[FONT=&quot]Side-effects [/FONT]</span><span style="color: #2B2622">[FONT=&quot]diarrhoea (discontinue treatment),[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]abdominal discomfort, oesophagitis, oesophageal[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]ulcers, taste disturbances, nausea, vomiting, antibiotic-[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]associated colitis; jaundice; leucopenia, eosinophilia,[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]and thrombocytopenia reported; polyarthritis[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]reported; rash, pruritus, urticaria, anaphylactoid[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]reactions, Stevens-Johnson syndrome, toxic epidermal[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]necrolysis, exfoliative and vesiculobullous[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]dermatitis reported; pain, induration, and abscess[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]after intramuscular injection; thrombophlebitis after[/FONT]</span></p><p> <span style="color: #2B2622">[FONT=&quot]intravenous injection[/FONT]</span></p></blockquote><p></p>
[QUOTE="pdnaclk, post: 11744937, member: 358615"] [B][COLOR=#0062A3][FONT="]CLINDAMYCIN[/FONT][/COLOR][/B] [COLOR=#0062A3][FONT="]Indications [/FONT][/COLOR][COLOR=#2B2622][FONT="]see notes above; staphylococcal bone and[/FONT][/COLOR] [COLOR=#2B2622][FONT="]joint infections, peritonitis; falciparum malaria (section[/FONT][/COLOR] [COLOR=#2B2622][FONT="]5.4.1)[/FONT][/COLOR] [COLOR=#0062A3][FONT="]Cautions [/FONT][/COLOR][COLOR=#2B2622][FONT="]discontinue immediately if diarrhoea or colitis[/FONT][/COLOR] [COLOR=#2B2622][FONT="]develops; monitor liver and renal function if[/FONT][/COLOR] [COLOR=#2B2622][FONT="]treatment exceeds 10 days, and in neonates and[/FONT][/COLOR] [COLOR=#2B2622][FONT="]infants; avoid rapid intravenous administration; avoid[/FONT][/COLOR] [COLOR=#2B2622][FONT="]in acute porphyria (section 9.8.2); [/FONT][/COLOR][COLOR=#2B2622][FONT="]interactions:[/FONT][/COLOR] [COLOR=#2B2622][FONT="]Appendix 1 (clindamycin)[/FONT][/COLOR] [COLOR=#0062A3][FONT="]Contra-indications [/FONT][/COLOR][COLOR=#2B2622][FONT="]diarrhoeal states; avoid injections[/FONT][/COLOR] [COLOR=#2B2622][FONT="]containing benzyl alcohol in neonates (see under[/FONT][/COLOR] [COLOR=#2B2622][FONT="]preparations below)[/FONT][/COLOR] [COLOR=#0062A3][FONT="]Pregnancy [/FONT][/COLOR][COLOR=#2B2622][FONT="]not known to be harmful[/FONT][/COLOR] [COLOR=#0062A3][FONT="]Breast-feeding [/FONT][/COLOR][COLOR=#2B2622][FONT="]amount probably too small to be[/FONT][/COLOR] [COLOR=#2B2622][FONT="]harmful but bloody diarrhoea reported in 1 infant[/FONT][/COLOR] [COLOR=#0062A3][FONT="]Side-effects [/FONT][/COLOR][COLOR=#2B2622][FONT="]diarrhoea (discontinue treatment),[/FONT][/COLOR] [COLOR=#2B2622][FONT="]abdominal discomfort, oesophagitis, oesophageal[/FONT][/COLOR] [COLOR=#2B2622][FONT="]ulcers, taste disturbances, nausea, vomiting, antibiotic-[/FONT][/COLOR] [COLOR=#2B2622][FONT="]associated colitis; jaundice; leucopenia, eosinophilia,[/FONT][/COLOR] [COLOR=#2B2622][FONT="]and thrombocytopenia reported; polyarthritis[/FONT][/COLOR] [COLOR=#2B2622][FONT="]reported; rash, pruritus, urticaria, anaphylactoid[/FONT][/COLOR] [COLOR=#2B2622][FONT="]reactions, Stevens-Johnson syndrome, toxic epidermal[/FONT][/COLOR] [COLOR=#2B2622][FONT="]necrolysis, exfoliative and vesiculobullous[/FONT][/COLOR] [COLOR=#2B2622][FONT="]dermatitis reported; pain, induration, and abscess[/FONT][/COLOR] [COLOR=#2B2622][FONT="]after intramuscular injection; thrombophlebitis after[/FONT][/COLOR] [COLOR=#2B2622][FONT="]intravenous injection[/FONT][/COLOR] [/QUOTE]
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