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Message: <blockquote data-quote="imhotep" data-source="post: 26721879" data-attributes="member: 562115">Yes the antibody generated immune response goes down with time. The antibody titers will get low whether these are vaccine generated or formed by natural infection.That's why you need a booster. But what we really need is a booster geared for the newer variants. Moderna has a booster but that doesn't really cover the Delta & Lambda.  Also it's still under trial. Pfizer also has a similar one and again on trial. These were developed for the initial variants.But our immune system also has T-cells which come to our rescue. T lymphocytes come in two broad types: CD8+ and CD4+.  Vaccines induce spike specific B and T cells that stays on , but no one know for exactly how long, as patients have to be continually tested over time to find out. As I have mentioned before T cell epitopes do not change in any variant. Basically when the antibody levels decline the T-cells provide us with protection against severe illness and death. There was an earlier post on T-cells.</blockquote>

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