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Message: <blockquote data-quote="imhotep" data-source="post: 28150946" data-attributes="member: 562115">UpdateAnother breakthrough has been reported by Tel Aviv University: A team of researchers from the university has demonstrated that antibodies isolated from the immune system of recovered COVID-19 patients are effective in neutralizing all known strains of the virus, including the Delta and the Omicron variants. According to the researchers, this discovery may eliminate the need for repeated booster vaccinations and strengthen the immune system of populations at risk.It's a continuation of a previous study started October 2020, and the researchers state -"In the current study, we proved that two other antibodies, TAU-1109 and TAU-2310, which bind the viral spike protein in a different area from the region where most of the antibodies were concentrated until now (and were therefore less effective in neutralizing the original strain) are actually very effective in neutralizing the Delta and Omicron variants. According to our findings, the effectiveness of the first antibody, TAU-1109, in neutralizing the Omicron strain is 92%, and in neutralizing the Delta strain, 90%. The second antibody, TAU-2310, neutralizes the Omicron variant with an efficacy of 84%, and the Delta variant with an efficacy of 97%."The TAU-1109 and TAU-2310 don't bind to the ACE2 receptor binding site, but to another region of the spike protein - an area of the viral spike that for some reason does not undergo many mutations - and they are therefore effective in neutralizing more viral variants. It's been tested with all the known COVID strains to date.The two antibodies, cloned in the laboratory at Tel Aviv University, were sent for tests to check their effectiveness against live viruses in laboratory cultures at the University of California San Diego, and against pseudoviruses in the laboratories of the Faculty of Medicine of Bar-Ilan University in the Galilee; the results were identical and equally encouraging in both tests.These developments will pave the way to effective antibody treatment, without the need to provide booster doses to the entire population every time there is a new variant. Antibodies in the first days following infection can stop the spread of the virus.</blockquote>

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