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Message: <blockquote data-quote="imhotep" data-source="post: 26368859" data-attributes="member: 562115">Good observation... <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite22" alt="(y)" title="Thumbs up    (y)" loading="lazy" data-shortname="(y)" /> It's a completely different approach. That's why I wrote "implementation is fairly complex". To many in this forum it will be useless information and for me to explain is not easy either. This scheme is not possible at all without the help of current gene technology. This is how they did it, as concise and as basic as possible.These scientists started off from the work done by a team of Tokyo University researchers. The Japanese made systematic set of deletions in the E. coli genome and showed that they can delete 29.7% of the genome, yet retain a viable, albeit slow growing organism. The base of the vaccine is this modified E coli organism. Hence the platform belongs to the Japanese.Then the US scientists designed a "plasmid" with a derived "AT expression cassette". This cassette is inserted to the E coli bacteria and the bacteria will happily transport it across. Bacterias do this quite often. This inserted cassette makes the bacteria to do a "surface expression" of the Covid fusion proteins. They used two types to test- one from Covid-19 (Beta Coronavirus) and another from PEDV (Alpha Coronavirus - Porcine Epidemic Diarrhoea Virus) - This is because the pig is the closest to us next to the non-human primates. The end result is that these modified E Coli will develop the Covid FP and the Porcine version of the FP on on it's surface.  It's no a simple task, but this team was successful in achieving it.When these bacteria gets injected, our body immune system will finally get rid of them, but in the interim our immune system will also identify the Covid FP that are carried by the E coli, and develop antibodies for it. If the vaccine is able to raise enough immune response hopefully, it's going to work. As I mentioned earlier the FP remains the same across the whole Coronaviridae line and hence it will work for any variant.PS: When we blindly go behind snake-oil concoctions and try to invoke various deities across the Universe against the Coronavirus, it's fascinating how these scientists use their logical thinking and using appropriate "science" to devise and explore hitherto unknown methods to combat it.<img src="/styles/default/xenforo/smilies/default/happy.gif"  class="smilie" loading="lazy" alt=":)" title="Happy    :)" data-shortname=":)" /></blockquote>

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