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<blockquote data-quote="Wal Bada" data-source="post: 5727662" data-attributes="member: 654"><p>Actually it's misnormer. It shoud be human-swine-bird flu.</p><p></p><p>Influenza virus undergoes minor change of it's genetic material (which is re percussed in it's surface proteins of the capsid. These proteins are the structures human immune system identifies and makes antibodies) called <strong>antigenic drift</strong>. Even if there is slight mismatch, human body can mount an antibody response for a antigenically drifted virus. (You can open some locks with a key with slight misfit) That's why there are no pandemics everyday with influenza.</p><p></p><p>Time and time, there is huge change due to exchange of genetic materials with other types of influenza viruses which infect other animals. This is called<strong> antigenic shift</strong>. Antigenically shifted virus is identified by human body after a delay, as it has totally changed it's suerface proteins. this H1N1 sero-type has genetic materials of swine and bird influenza viruses in combination to human one. </p><p></p><p>So you could figure it out that vaccines are only partially protective against influenza.</p></blockquote><p></p>
[QUOTE="Wal Bada, post: 5727662, member: 654"] Actually it's misnormer. It shoud be human-swine-bird flu. Influenza virus undergoes minor change of it's genetic material (which is re percussed in it's surface proteins of the capsid. These proteins are the structures human immune system identifies and makes antibodies) called [B]antigenic drift[/B]. Even if there is slight mismatch, human body can mount an antibody response for a antigenically drifted virus. (You can open some locks with a key with slight misfit) That's why there are no pandemics everyday with influenza. Time and time, there is huge change due to exchange of genetic materials with other types of influenza viruses which infect other animals. This is called[B] antigenic shift[/B]. Antigenically shifted virus is identified by human body after a delay, as it has totally changed it's suerface proteins. this H1N1 sero-type has genetic materials of swine and bird influenza viruses in combination to human one. So you could figure it out that vaccines are only partially protective against influenza. [/QUOTE]
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