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Message: <blockquote data-quote="Hyaenidae" data-source="post: 28123621" data-attributes="member: 530392"><img src="https://i.imgur.com/BmdWvyZ.jpg" alt="" class="fr-fic fr-dii fr-draggable " style="" /><h3>KX-826 Phase 2 Data Results</h3>The important statistical data results from Kintor’s KX-826 pyrilutamide phase 2 trial in males is:<ul> <li data-xf-list-type="ul">The trial comprised 120 male subjects with Norwood levels of 3V, 4, and 5.</li> <li data-xf-list-type="ul">Cohorts included KX-826 2.5mg BID, 5mg QD, 5mg BID, and Placebo QD, BID.</li> <li data-xf-list-type="ul">Primary endpoint was non-vellus target area hair count (TAHC) change from baseline to week 24.</li> <li data-xf-list-type="ul">After 14 days of topical use, the blood concentration levels of KX-826 were 0.3 – 4.1 ng/ml, and its metabolite KX-982’s levels were 0.4 – 10.4 ng/ml.</li> <li data-xf-list-type="ul">The incidence of adverse drug reactions was 16.1%, with the most common being pruritus or itchy skin. No serious adverse events or serious adverse drug reactions were reported.</li> <li data-xf-list-type="ul">The most efficacious results were obtained in the group receiving 5mg of KX-826 BID (twice daily) which showed a 15.34 hair per cm² increase in TAHC above the placebo group, and a total increase of 22.73 hairs per cm² in TAHC compared to baseline.</li> </ul>These results will certainly be well received by the community of people seeking new treatments for hair loss and hair regrowth. Showing a 22 hair per cm² increase in non-vellus hair count, these results are easily comparable to past studies of oral finasteride. As a reminder, Kintor is also currently engaged in other KX-826 clinical trials, including a female phase 2 trial and male phase 3 trial in China, as well as a male phase 2 trial in the US.tl;dr : A new drug as efficacious as oral finasteride without the side effects of finasteride.[USER=181982]@Heshan Daminda[/USER] [USER=574859]@emoji diaries[/USER] </blockquote>

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