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Message: <blockquote data-quote="x-pert" data-source="post: 697964" data-attributes="member: 837">MDMA (3,4-methylenedioxy-N-methylamphetamine), most commonly known today by the street name ecstasy, (often abbreviated to E, X, or XTC) is a semisynthetic entactogen of the phenethylamine family. It is considered a recreational drug, and has long had a strong association with the rave culture. MDMA is illegal in most countries, and its possession, manufacture or sale may result in criminal prosecution. (wikipedia)<img src="http://upload.wikimedia.org/wikipedia/commons/thumb/b/ba/MDMA.png/220px-MDMA.png" alt="" class="fr-fic fr-dii fr-draggable " style="" />Never Ever try these kinda stuff guys... <img src="/styles/default/xenforo/smilies/default/happy.gif"  class="smilie" loading="lazy" alt=":)" title="Happy    :)" data-shortname=":)" /><img src="http://upload.wikimedia.org/wikipedia/commons/e/e3/Ecstacy_monogram.jpg" alt="" class="fr-fic fr-dii fr-draggable " style="" />There exists a significant risk for chronic physical harm arising from ecstasy use. Despite the fact that the chief executive of the UK Medical Research Council stated MDMA was "on the bottom of the scale of harm", and the Science & Technology Committee rated it of lower concern than for alcohol, tobacco, and cannabis, when examining the harmfulness of any given drug, the UK study placed great weight on the risk for acute physical harm, the propensity for physical and psychological dependency on the drug and the negative familial and societal impacts of the drug-- MDMA scores relatively low on these dimensions of harm, this is why it has an overall harm score lower than even alcohol.[16][17] Nevertheless, there is evidence (based on monkey & mice models) that- even in a single dose [18]- ecstasy leads to permanent axonal damage in the cortex and hippocampus of the mammalian brain-- under the UK study (Nutt et al.) this dimension of harm is called "Chronic physical harm" if present humans and it is underestimated because the biological harms are subtle, the long-term effects in humans are unknown and the experts consulted are clinical psychiatrists, not research-level neuroscientists and psychologists. [18] These areas are known to be associated with the regulation of emotion and the retrieval of memory. More recent studies have demonsrated the toxic effects on human serotoninergic neurons and the deficits in human memory [19] [20][21] For the most current scientific understanding of the toxicity of ecstasy see the January 2007 issue of Pyscho-pharmacology entitled "A contemporary view of MDMA"</blockquote>

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