A copy of a post I made on 01 Feb 2021 FYI...
This is an interesting documentary on how the village of Eyam, in Derbyshire
survived the Black Death. How the
CCR5-Delta32 mutation is linked to HIV immunity.
Also those with the Delta mutation aren't get seriously affected by Covid-19 or simply they are not infected. This is not mentioned in the video but scientists are aware and trying to ascertain whether a CCR 5 (Chemokine Receptor-5) blocking antibody could be developed or on how the CCR5 can be targeted to develop a Covid-19 drug.
In the mid-1990s, it was discovered that possession of the CCR5-Δ32 allele leads ‘to nearly complete resistance to HIV-1 infection’ and AIDS. This genetic mutation shows strong geographical traits: while supposedly absent among Africans, Amerindians and East Asians, it is found in up to 14%, in certain northern populations of Eurasia, and more recently this figure has been estimated to be as high as 18%. Moreover, within Eurasia the frequency of this gene shows a north-to-south cline, with its highest rates in north-eastern Europe. Subsequent research has largely sustained these geographical patterns, although geneticists now find that the allele was not wholly absent from non-Eurasian populations, but is also detected in people of African descent.
In a survey of CCR5-Δ32 allele frequencies in 38 ethnic populations with 4166 subjects, the absence of the allele outside Eurasia, and a north-south gradient within Europe, were affirmed. Frequencies for Asia were very low (0% for Chinese descendents, 0% for Georgians and 3.4% for Uzbeks—the highest for any area of Asia, unless Russia is assumed to be Asian; no distinction was made between Asiatic and European, or north and south Russia.