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<blockquote data-quote="imhotep" data-source="post: 26813995" data-attributes="member: 562115"><p>Initially, there was a delay. The funds released by all the major Governments in the World was to develop a vaccine, and all jumped along on the vaccine bus.</p><p>There wasn't funds for drug development. The drug companies did pursue but unless the money is held in front of them, doesn't go a long way.</p><p></p><p>Only with the new US Government, they released funds for drug development because the committee report specifically mentioned the lack of effort towards drug development.</p><p></p><p>Currently, here's a consortium of 20 or 25 collectively working on this. With viruses it's not easy. Pathogens like Bacteria, Parasite or fungi can be easily targeted by drugs because of their cellular nature. In contrast a Virus is different. Viruses do not possess a cellular anatomy and has usually has a compact genome and thus difficult to find a druggable target. On top of all this, the viruses mutate, rapidly replicate in millions and the anti-viral for Covid has to be extremely effective. If some group is lucky, then it's<strong> most likely</strong> that they will find a pan-corona virus anti-viral rather than one that would only specifically target Covid.</p><p></p><p>There are a couple of drugs from Pfizer under trial. One uses their MPro platform, developed during the SARS epidemic. There was a drug developed by the Georgia University that stops the virus transmission within 24 hours, and a lot more. I had posts on these before.</p><p></p><p>But sadly the "Silver Bullet" hasn't really been found yet. But one day, hopefully, someone will find a breakthrough. Hope it's not very far away.</p></blockquote><p></p>
[QUOTE="imhotep, post: 26813995, member: 562115"] Initially, there was a delay. The funds released by all the major Governments in the World was to develop a vaccine, and all jumped along on the vaccine bus. There wasn't funds for drug development. The drug companies did pursue but unless the money is held in front of them, doesn't go a long way. Only with the new US Government, they released funds for drug development because the committee report specifically mentioned the lack of effort towards drug development. Currently, here's a consortium of 20 or 25 collectively working on this. With viruses it's not easy. Pathogens like Bacteria, Parasite or fungi can be easily targeted by drugs because of their cellular nature. In contrast a Virus is different. Viruses do not possess a cellular anatomy and has usually has a compact genome and thus difficult to find a druggable target. On top of all this, the viruses mutate, rapidly replicate in millions and the anti-viral for Covid has to be extremely effective. If some group is lucky, then it's[B] most likely[/B] that they will find a pan-corona virus anti-viral rather than one that would only specifically target Covid. There are a couple of drugs from Pfizer under trial. One uses their MPro platform, developed during the SARS epidemic. There was a drug developed by the Georgia University that stops the virus transmission within 24 hours, and a lot more. I had posts on these before. But sadly the "Silver Bullet" hasn't really been found yet. But one day, hopefully, someone will find a breakthrough. Hope it's not very far away. [/QUOTE]
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