Two more variants are in circulation - B.1.525 & B.1.526
B.1.525
Sub-lineage of: B.1
Earliest sequence: 2020-12-15 (England/CAMC-C769B3/2020)
Most recent sequence: 2021-01-28 (England/MILK-119FD0B/2021)
Countries circulating: England (28), Nigeria (7), USA (7), France (5), Canada (4), Ghana (4), Japan (4), Jordan (2), Belgium (1), Italy (1), Spain (1)
Characterised by spike mutations: E484K, Q677H, F888L, 69-70 deletion, 144 deletion and 9 nucleotide mutation in nsp6 (as seen in B.1.1.7, B.1.351, P.1).
B.1.526
A lineage predominantly circulating in New York but with a few exports to other countries. Characterised by spike mutations T95I and D253G, plus others. The most frequent spike mutation pattern is L5F T95I D253G E484K D614G A701V, with a smaller fraction having S477N instead of E484K. Spike mutation E484K is present in about half of this lineage (as of 2021-02-10)
This B.1.526 variant appeared in late November 2020, and alarmingly isolates from this lineage account for about 5% of coronavirus genomes sequenced and deposited from New York during late January 2021 and scientists are worried that this number is growing exponentially.
B.1.525
Sub-lineage of: B.1
Earliest sequence: 2020-12-15 (England/CAMC-C769B3/2020)
Most recent sequence: 2021-01-28 (England/MILK-119FD0B/2021)
Countries circulating: England (28), Nigeria (7), USA (7), France (5), Canada (4), Ghana (4), Japan (4), Jordan (2), Belgium (1), Italy (1), Spain (1)
Characterised by spike mutations: E484K, Q677H, F888L, 69-70 deletion, 144 deletion and 9 nucleotide mutation in nsp6 (as seen in B.1.1.7, B.1.351, P.1).
B.1.526
A lineage predominantly circulating in New York but with a few exports to other countries. Characterised by spike mutations T95I and D253G, plus others. The most frequent spike mutation pattern is L5F T95I D253G E484K D614G A701V, with a smaller fraction having S477N instead of E484K. Spike mutation E484K is present in about half of this lineage (as of 2021-02-10)
This B.1.526 variant appeared in late November 2020, and alarmingly isolates from this lineage account for about 5% of coronavirus genomes sequenced and deposited from New York during late January 2021 and scientists are worried that this number is growing exponentially.
