Reply to thread

Message: <blockquote data-quote="imhotep" data-source="post: 30285449" data-attributes="member: 562115">It's safe to eat because virus cannot enter into human cells. The exact mechanism is not yet fully understood but studies show that ASFV enters host cells through multiple mechanisms. This includes a receptor-dependent form of endocytosis, known as Clathrin-Mediated Endocytosis (CME) , and is dependent on temperature, energy, cholesterol and low pH. Clathrin-mediated endocytosis (CME) is a common entry pathway for many viruses, including large DNA viruses.ASF virus targets macrophages and monocytes in swine cells for entry and replication, although the identity of cellular receptors targeted by the virus for host cell entry are unknown. It is possible that the virus uses some specialized receptors on the host cell surface that are absent in non-susceptible species or certain steps in viral replication or maturation may not be supported in non-sensitive species.So far, only domestic pigs and wild boars (warthogs and bushpigs) are susceptible to the virus,PS: Low levels of ASF virus replication in human cell lines like Vero and HEK293T cells have been achieved by continuous passaging and adaptation. However, the adapted virus is less infectious in swine macrophages compared to the wild-type strain.<a href="https://imgbox.com/oXh9rUB9" target="_blank"><img src="https://thumbs2.imgbox.com/bf/41/oXh9rUB9_t.jpg" alt="" class="fr-fic fr-dii fr-draggable " style="" /></a></blockquote>

Verification: Payakata winadi keeyak tibeda?

Top Bottom