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Message: <blockquote data-quote="imhotep" data-source="post: 26654976" data-attributes="member: 562115">First of all, note that Cancer treatment vaccines are different to other standard vaccines that we know about. Cancer vaccines try to get the immune system to mount an attack against cancer cells in the body. Instead of preventing disease, they are meant to get the immune system to attack a disease that already exists.This particular BNT111 vaccine targets melanoma. There are plans to test it further with non-small cell lung cancer (NSCLC). Another contender from Merck was used to treat metastatic small cell lung cancer (SCLC) and advanced lung cancer. It's "Keytruda" and was sometimes used along with Platinum chemotherapy. Also it was tested and used with Head & Neck Squamous Cell Cancer and Classical Hodgkin Lymphoma. It was claimed to be resulting in 20 percent improved survival at one year.However, sadly Merck withdrew the product voluntarily on the 01 March 2021. The move came following the US Food and Drug Administration’s (FDA’s) recent crackdown on drugs approved through accelerated pathways without the required post-marketing data.The FDA keeps tab on these and if the developer doesn't meet their criteria the developer could be in big trouble. Merck met its progression-free survival primary endpoint but missed its other endpoint of overall survival (OS). This led to the voluntary withdrawal. It's said that Merck is working with the FDA to sort this out in the coming few months. I haven't heard about any progress lately. In the third quarter of 2020 alone, this drug achieved sales of $3.7bn and used in several countries.</blockquote>

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