Factors that influence the Pfizer vaccine long term immunity.

imhotep

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  • Mar 29, 2017
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    The Japanese scientists claim that there are several risk factors involved with the long term immunity of the Pfizer vaccine. Old age and smoking were amongst those with some of the lowest antibody titers. Also the gender counts. Women more than men were also more likely to experience a rapid decline in antibody levels 3 to 6 months after receiving their second Pfizer-BioNTech dose.

    Antibody titers against SARS-CoV-2 declined at a median rate of -29.4%. While age did not influence the rate of decline, sex did. Women experienced a 6.5% faster rate of decline than men. The median rate of change in antibody titers was 31.6% in women. In contrast, men showed a -25.1% rate of change.

    They are also suggesting to use an individualized vaccination schedule, or alternatively using an adenovirus-based vaccine than an mRNA vaccine as the booster.

    The US has authorized a third dose for those over 18 who received their second vaccination at least six months ago.
     

    imhotep

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  • Mar 29, 2017
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    Even if these companies can come up with a 'one-shot vaccine' or something similar, I don't think they will, why shoot yourself in the leg when you can charge that sweet sweet booster shot money... Maybe I am being too cynical...
    It's not a single shot vaccine we need. It's a pan-coronavirus (or a Universal Cornavirus) vaccine - a one that works on all variants - present & future.
    Several of these are in the development or test stages but will only be available in 2023 assumimg these are going to be successful.

    Even then we probably need boosters, simply because the vaccine efficacy dwindles over time. It's good money for the vaccine makers and also the PCR testing labs worldwide.
     
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