The Japanese scientists claim that there are several risk factors involved with the long term immunity of the Pfizer vaccine. Old age and smoking were amongst those with some of the lowest antibody titers. Also the gender counts. Women more than men were also more likely to experience a rapid decline in antibody levels 3 to 6 months after receiving their second Pfizer-BioNTech dose.
Antibody titers against SARS-CoV-2 declined at a median rate of -29.4%. While age did not influence the rate of decline, sex did. Women experienced a 6.5% faster rate of decline than men. The median rate of change in antibody titers was 31.6% in women. In contrast, men showed a -25.1% rate of change.
They are also suggesting to use an individualized vaccination schedule, or alternatively using an adenovirus-based vaccine than an mRNA vaccine as the booster.
The US has authorized a third dose for those over 18 who received their second vaccination at least six months ago.
Antibody titers against SARS-CoV-2 declined at a median rate of -29.4%. While age did not influence the rate of decline, sex did. Women experienced a 6.5% faster rate of decline than men. The median rate of change in antibody titers was 31.6% in women. In contrast, men showed a -25.1% rate of change.
They are also suggesting to use an individualized vaccination schedule, or alternatively using an adenovirus-based vaccine than an mRNA vaccine as the booster.
The US has authorized a third dose for those over 18 who received their second vaccination at least six months ago.
