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Message: <blockquote data-quote="Juliakhanam" data-source="post: 8134905" data-attributes="member: 303069">Actually,the heart rate is under the direct influence of the central  nervous system : Autonomic,consisting of sympathetic and parasympathetic  systems : As well, several., power full neuro-transmitters that are  influenced by the autonomic system. Many cardiac drugs, act upon heart  rates directly by influencing these chemicals and their receptors.What I believe you are referring to is "automaticity" of the Sinoatrial(SA, pacemaker) node and to some extent, the AVnode.: Given no other influences, they have an "inherent rate" or  independent rate, as you described. As pointed out by another  contributor, the AV node can initiate an "inherent" rate, if the SA node  fails or it's impulses (depolarizrion) are not conducted ( i.e. heart  block): However,it's inherent rate is much slower(40-60 BPM) than the SA  node (60-80 BPM).There are many, many disease states that alter this schematic or  substitute pacemakers, and conduction pathways but it makes my heart  rate increase just thinking about them.</blockquote>

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