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Incidence of Myocarditis after mRNA vaccines - Israeli Data.
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<blockquote data-quote="imhotep" data-source="post: 26974798" data-attributes="member: 562115"><p>A research group led by Dr. Guy Witberg from the Beilinson Hospital in Petah Tikva and Tel Aviv University conducted a retrospective cohort study was based on the database of the single and largest health care institution in Israel – Clalit Health Services. These were vaccinated between December 20, 2020, and May 24, 2021 during the Israeli vaccination campaign.</p><p></p><p>Just published report in the NEJM states that - The estimated incidence of myocarditis among patients that have received at least one dose of the Pfizer-BioNTech (BNT162b2) mRNA vaccine against coronavirus disease 2019 (COVID-19) was 2.13 cases per 100,000 persons, primarily affecting young men and presenting mostly as mild or moderate illness.</p><p></p><p><span style="font-size: 15px"><strong>RESULTS</strong></span></p><p></p><p>Among more than 2.5 million vaccinated HCO members who were 16 years of age or older, 54 cases met the criteria for myocarditis. The estimated incidence per 100,000 persons who had received at least one dose of vaccine was 2.13 cases (95% confidence interval [CI], 1.56 to 2.70). The highest incidence of myocarditis (10.69 cases per 100,000 persons; 95% CI, 6.93 to 14.46) was reported in male patients between the ages of 16 and 29 years. A total of 76% of cases of myocarditis were described as mild and 22% as intermediate; 1 case was associated with cardiogenic shock. After a median follow-up of 83 days after the onset of myocarditis, 1 patient had been readmitted to the hospital, and 1 had died of an unknown cause after discharge. Of 14 patients who had left ventricular dysfunction on echocardiography during admission, 10 still had such dysfunction at the time of hospital discharge. Of these patients, 5 underwent subsequent testing that revealed normal heart function.</p><p></p><p><span style="font-size: 15px"><strong>CONCLUSIONS</strong></span></p><p></p><p>Among patients in a large Israeli health care system who had received at least one dose of the BNT162b2 mRNA vaccine, the estimated incidence of myocarditis was 2.13 cases per 100,000 persons; the highest incidence was among male patients between the ages of 16 and 29 years. Most cases of myocarditis were mild or moderate in severity.</p></blockquote><p></p>
[QUOTE="imhotep, post: 26974798, member: 562115"] A research group led by Dr. Guy Witberg from the Beilinson Hospital in Petah Tikva and Tel Aviv University conducted a retrospective cohort study was based on the database of the single and largest health care institution in Israel – Clalit Health Services. These were vaccinated between December 20, 2020, and May 24, 2021 during the Israeli vaccination campaign. Just published report in the NEJM states that - The estimated incidence of myocarditis among patients that have received at least one dose of the Pfizer-BioNTech (BNT162b2) mRNA vaccine against coronavirus disease 2019 (COVID-19) was 2.13 cases per 100,000 persons, primarily affecting young men and presenting mostly as mild or moderate illness. [SIZE=4][B]RESULTS[/B][/SIZE] Among more than 2.5 million vaccinated HCO members who were 16 years of age or older, 54 cases met the criteria for myocarditis. The estimated incidence per 100,000 persons who had received at least one dose of vaccine was 2.13 cases (95% confidence interval [CI], 1.56 to 2.70). The highest incidence of myocarditis (10.69 cases per 100,000 persons; 95% CI, 6.93 to 14.46) was reported in male patients between the ages of 16 and 29 years. A total of 76% of cases of myocarditis were described as mild and 22% as intermediate; 1 case was associated with cardiogenic shock. After a median follow-up of 83 days after the onset of myocarditis, 1 patient had been readmitted to the hospital, and 1 had died of an unknown cause after discharge. Of 14 patients who had left ventricular dysfunction on echocardiography during admission, 10 still had such dysfunction at the time of hospital discharge. Of these patients, 5 underwent subsequent testing that revealed normal heart function. [SIZE=4][B]CONCLUSIONS[/B][/SIZE] Among patients in a large Israeli health care system who had received at least one dose of the BNT162b2 mRNA vaccine, the estimated incidence of myocarditis was 2.13 cases per 100,000 persons; the highest incidence was among male patients between the ages of 16 and 29 years. Most cases of myocarditis were mild or moderate in severity. [/QUOTE]
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