India New Virus OutBreak

emoboy

Well-known member
  • Oct 1, 2015
    2,232
    2,896
    113
    අලුත් virus එකක් spread වෙන්න පටන් අරන් kerala වල. තාම deads 2යි. ඉක්මනට spread වෙනවලු. මුලින්ම corona එකත් මෙහෙම තමා ආවෙ. Spread උනා ඉක්මනට

     

    pramodh87

    Well-known member
  • Oct 11, 2007
    3,774
    9,789
    113
    අලුත් virus එකක් spread වෙන්න පටන් අරන් kerala වල. තාම deads 2යි. ඉක්මනට spread වෙනවලු. මුලින්ම corona එකත් මෙහෙම තමා ආවෙ. Spread උනා ඉක්මනට


    උබ අද ද දන්නේ...😂
     
    • Like
    Reactions: NRTG

    Sri_Sampath

    Well-known member
  • Jan 26, 2010
    14,704
    12,739
    113
    Nipah virus (NiV) was first discovered in 1999 following an outbreak of disease in pigs and people in Malaysia and Singapore. This outbreak resulted in nearly 300 human cases and more than 100 deaths, and caused substantial economic impact as more than 1 million pigs were killed to help control the outbreak.

    While there have been no other known outbreaks of NiV in Malaysia and Singapore since 1999, outbreaks have been recorded almost annually in some parts of Asia since then—primarily in Bangladesh and India. The virus has been shown to spread from person-to-person in these outbreaks, raising concerns about the potential for NiV to cause a global pandemic.

    CDC
     

    imhotep

    Well-known member
  • Mar 29, 2017
    14,824
    8
    35,334
    113
    Nipah has around 70% mortality rate, Covid had 3%: ICMR

    කොරෝන වගේ වෙන එකක් නෑනෙ. ස්ප්‍රෙඩ් වෙන එක අඩුවෙයි මැරෙනව වැඩි නිසා. @imhotep @emoji diaries ගෙන් හරියටම අහගමු

    I replied on the very first thread posted on this outbreak...copied that a few bits extra.

    Nipah raises it's head in India from time to time. Mostly in Kerala. Origin of Nipah was Malaysia in 1998. It's a member of the family Paramyxoviridae, genus Henipavirus. Mortality between 40% to 70%.
    The viral genome consists of a non-segmented negative sense single-stranded RNA of approximately 18.2 kb long which encodes six structural proteins.

    Paramyxoviruses are host-specific, and several are pathogenic to humans, including NiV, measles virus, mumps virus, Hendra virus (HeV), and several parainfluenza viruses. NiV has a broad host range that includes humans, bats, pigs, sheep, goats, dogs, cats, and horses.
    Since the initial detection, three countries described single or sporadic reoccurring outbreaks: Bangladesh (the first outbreak was in 2001, and then there were nine subsequent outbreaks till 2010 and 2011), India (2001, 2007, 2018, 2019, 2021) and the Philippines in 2014. In Bangladesh and India, the most likely sources of infection were fruits or fruit products (such as raw date palm sap) contaminated with urine or saliva from infected fruit bats. Human-to-human transmission was also reported. In the Philippines, the most commonly described routes of transmission to humans were direct exposure to infected horses, contact with contaminated materials during the slaughtering of sick horses, or consumption of raw or undercooked meat from infected horses.

    The Indian strain (I) is different from the genotypes found in Bangladesh (B) and Malaysia (M), the two major strains with a common descent.

    The incubation period of NiV generally ranges between 4–21 days but can be longer. In Malaysia incubation upto two months was noted. Infected persons remain infectious till 21 days after the onset of symptoms.

    The initial signs and symptoms of NiV infection are nonspecific, which is why it is often misdiagnosed at first. RT-PCR nasal/throat swab needed.
    Currently no treatment other than management. However, a monoclonal antibody is under human trials.
    Several vaccines are under development including one mRNA vaccine, one using a protein from the closely related Hendra virus and one using a harmless vesicular stomatitis virus to deliver a Nipah virus protein.

    Containment and contact tracing is the key. The last time the Indians successfully did it in a month. The Indian NIV report that the footprint of Nipah virus in bats in 10 out of the 16 States. However, in Kerala, the human habitations are either close to the forest or within the forests. Hence the increased repeat incidences. It's also said that in Kerala the monitoring and reporting system is well managed.
     

    RandomGuy

    Well-known member
  • Oct 15, 2014
    17,370
    16,212
    113
    උදයන්ගයා තාම දන්නේ නැතුව ඇති නැත්තම් මෙලහකටත් කෙරලයෙන් සංචාරකයෝ කණ්ඩායමක් ගෙන්වලා :P

    මිනී ගොඩ ගහලා පෙන්නලා විදේශ ආධාර ගන්න පුළුවන්ද කියලා බලන්න කරපු විද්‍යාත්මක පරීක්ෂණයක් ඒක. 😎
     

    NRTG

    Well-known member
  • Oct 19, 2019
    40,647
    197,666
    113
    Colombo, Sri Lanka
    I replied on the very first thread posted on this outbreak...copied that a few bits extra.

    Nipah raises it's head in India from time to time. Mostly in Kerala. Origin of Nipah was Malaysia in 1998. It's a member of the family Paramyxoviridae, genus Henipavirus. Mortality between 40% to 70%.
    The viral genome consists of a non-segmented negative sense single-stranded RNA of approximately 18.2 kb long which encodes six structural proteins.

    Paramyxoviruses are host-specific, and several are pathogenic to humans, including NiV, measles virus, mumps virus, Hendra virus (HeV), and several parainfluenza viruses. NiV has a broad host range that includes humans, bats, pigs, sheep, goats, dogs, cats, and horses.
    Since the initial detection, three countries described single or sporadic reoccurring outbreaks: Bangladesh (the first outbreak was in 2001, and then there were nine subsequent outbreaks till 2010 and 2011), India (2001, 2007, 2018, 2019, 2021) and the Philippines in 2014. In Bangladesh and India, the most likely sources of infection were fruits or fruit products (such as raw date palm sap) contaminated with urine or saliva from infected fruit bats. Human-to-human transmission was also reported. In the Philippines, the most commonly described routes of transmission to humans were direct exposure to infected horses, contact with contaminated materials during the slaughtering of sick horses, or consumption of raw or undercooked meat from infected horses.

    The Indian strain (I) is different from the genotypes found in Bangladesh (B) and Malaysia (M), the two major strains with a common descent.

    The incubation period of NiV generally ranges between 4–21 days but can be longer. In Malaysia incubation upto two months was noted. Infected persons remain infectious till 21 days after the onset of symptoms.

    The initial signs and symptoms of NiV infection are nonspecific, which is why it is often misdiagnosed at first. RT-PCR nasal/throat swab needed.
    Currently no treatment other than management. However, a monoclonal antibody is under human trials.
    Several vaccines are under development including one mRNA vaccine, one using a protein from the closely related Hendra virus and one using a harmless vesicular stomatitis virus to deliver a Nipah virus protein.

    Containment and contact tracing is the key. The last time the Indians successfully did it in a month. The Indian NIV report that the footprint of Nipah virus in bats in 10 out of the 16 States. However, in Kerala, the human habitations are either close to the forest or within the forests. Hence the increased repeat incidences. It's also said that in Kerala the monitoring and reporting system is well managed.
    BUMP