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Message: <blockquote data-quote="imhotep" data-source="post: 29922571" data-attributes="member: 562115">The core of this breakthrough is the creation of nanoscale structures built with DNA, called DNA origami. Specifically, the nanobots’ three-dimensional DNA origami design allows them to be both pH-sensitive and capable of autonomous function. The head of the nanorobot contains a cavity that physically hides six cytotoxic ligands arranged in a hexagonal pattern. These peptides are designed to bind to and activate death receptors on cancer cells. Under normal physiological conditions, including environments with an acidic pH of 7.4, the ligands remain concealed within the nanorobot, rendering it inert and harmless. However, at a pH level of 6.5, typical of cancerous tissues, a “kill switch” is triggered, and the DNA structures unfold to reveal cytotoxic ligands. The ligands then cluster death receptors on the surface of cancer cells, triggering apoptosis or programmed cell death.<a href="https://imgbox.com/HAy5V8Lx" target="_blank"><img src="https://thumbs2.imgbox.com/11/b8/HAy5V8Lx_t.jpg" alt="" class="fr-fic fr-dii fr-draggable " style="" /></a></blockquote>

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