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Message: <blockquote data-quote="imhotep" data-source="post: 26623792" data-attributes="member: 562115">Yes.. Israeli Health reported that it seems that the Delta variants can bypass the vaccines but too early to draw conclusions about the vaccine's effectiveness against serious illness.Analysis of their data shows that in the past month, the coronavirus vaccine has proven to be 64% effective against symptomatic infection by the Delta variant. Among those infected, almost half are schoolchildren, a significant percentage of whom were already fully vaccinated.The unique mutations in the Delta variant mean the virus can escape the immune system to some extent and this is why the reduced efficacy in almost all the current vaccines.The Israeli data shows 64% for mRNA vaccines, the Brazilian data shows less than 40% for the Chinese vaccines based on P.1 variant and will be lower still for Delta. No one did a proper study.Only the future DNA vaccines and vaccines targeting other areas of the virus would possibly work with the variants. There are several DNA based vaccines on trial across the world from USA to Australia.FYI.  Here's an extract from one of my older posts on Covid vaccines...."I did mention here several times that there's a major flaw in all the Covid vaccines - which is targeting of the Spike protein. The Wuhan Virus keeps on changing it's outer coat, creating variants, which in turn affects the efficacy of the vaccines which were developed with the sequence of the original strain.Also I mentioned that several vaccine developers are moving into Generation 2 vaccines, dropping the S- protein and trying to target something else that doesn't change with the variants. There are a couple of teams who uses different approaches and I will briefly mention one of them that had done animal trials.The development of a universal vaccine is not an easy task. All coronaviruses use what's known as trimeric Type I fusion proteins to bind and enter host cells. The S protein is cleaved into two parts called S1 and S2. The S1 part is the Receptor Binding Domain (RBD) and that's the one that locks into the ACE2 receptors. The S2 part includes a "Fusion Peptide" (FP) which allows the virus to fuse into our cell membranes. The FP part on S2 does not change across the whole Coronaviridae family. It stays 93% the same across ALL the coronaviruses.The new vaccine targets this FP and even if the virus can bind into the ACE2 receptor, it cannot fuse with the cell membranes, thus making it ineffective. Note that across all the variants the FP remains the same and thus the vaccine is variant independent. The same vaccine will work across all the variants."</blockquote>

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