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Message: <blockquote data-quote="imhotep" data-source="post: 26624594" data-attributes="member: 562115">You can mix AZ or Sputnik (they both are adenovirus vector vaccines) with Pfizer/Moderna (mRNA vaccines) - you get the best of both worlds.The Philippines was doing a study with the Chinese vaccines (inactivated), but I haven't read about anything further on this. In any case in the Gulf areas, they have given a booster shot from Moderna for those who didn't show enough antibodies even after three Chinese vaccine shots.Copy of one of my older post...Results of the Spanish Combivac trial."A study done by the Carlos III Health Institute in Spain, has concluded that the under-60s who have already received one shot of the Oxford-AstraZeneca vaccine can be safely administered the Pfizer-BioNTech medication for their second dose.The study named CombivacS had a total of 772 volunteers and 472 of them received the Pfizer as their second shot, and 221 were used as a control group who didn't receive the second jab.The study proved that second dose using the Pfizer vaccine is “highly immunogenic and safe.” The vaccinated group saw its immune response multiply by 120 a week after this second dose, while the control group’s level held steady. When the serum of the patients was mixed in the laboratory with samples of the coronavirus the neutralizing defense response was shown to multiply by seven. In the equivalent trials with a second dose of AstraZeneca, this response was multiplied by three.Basically by combining these two vaccines, the neutralizing antibody response shot up by 7 times.PS: I always argued for mixing of the vaccines because the combination could offer an higher efficacy than using the booster shot of the same vaccine. This is what the Russians were doing from the very beginning. Gameleya uses TWO vaccines, the primer uses rAd26 and the booster uses rAd5 - two different adeno-viruses as the transport mechanism (vectors). Though they didn't admit or say - This it was really a mix and match.This is possible because all current vaccines target the S-protein. Except the Chinese ones and Bharat Bio-Tech. These are inactivated, and hence cannot say much unless tested. Also there's one more inactivated vaccine due from Europe."</blockquote>

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