The first US patent to University of Colombo
With the intension of value addition to Sri Lanka’s natural resources by showcasing the benefits of coupling natural science with Biotechnology, a National Research Council funded project was conducted by a team of academics of the Faculties of Science and Medicine. A wide survey of macrofungi was conducted and the collection was screened for anticancer activity. Among a number of other compounds yielded, a compound extracted from the mushroom Fulviformes fastuosus was found to show significant anticancer activity against Rhabdomyosarcoma, an aggressive and highly malignant form of childhood cancer.
The uniqueness of this compound, Inoscavin A, is that: (i) it is active at nanogram levels where the control drug was active at mg levels (ii) Non detectable toxicity to normal cells.
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