Maxillary Osteosarcoma Associated With a Dental Implant
Report of a Case and Review of the Literature Regarding Implant-Related Sarcomas
H. Stan McGuff, DDS, Josefine Heim-Hall, MD, F. Christopher Holsinger, MD, Archie A. Jones, DDS, Daniel S. O’Dell, DDS, MS and Adam C. Hafemeister, BS
ABSTRACT
Background: The development of malignant neoplasms has been reported as a common complication of the use of implanted biomaterials. The majority of these cases have been sarcomas related to orthopedic hardware. The authors present the first reported case of a sarcoma arising in association with a dental implant.
Case Description: A 38-year-old woman developed a low-grade chondroblastic osteosarcoma of the right maxilla 11 months after receiving a titanium dental implant. She was treated with systemic chemotherapy and then a maxillary resection. As of this publication, 47 months later, she is alive and disease-free.