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    After 60 years, new hidden brain pathway found - How Metformin works.

    Hopefully new treatments that target this pathway will be developed. Only a small dose needs to trigger the brain into action.
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    After 60 years, new hidden brain pathway found - How Metformin works.

    Metformin is the most commonly prescribed antidiabetes drug, yet its precise mechanism of action remains controversial. Previous studies have suggested that metformin acts peripherally by reducing hepatic glucose output and altering gut functions. Here, we report a neural mechanism via the...
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    Scientists Unveil New Weapon That Kills Cancer Without the Immune System.

    Challenging Over 150 Years of Immunotherapy.... Two bacteria working in harmony show powerful antitumor effects. The approach could transform treatment for immunocompromised patients. A research team led by Professor Eijiro Miyako at the Japan Advanced Institute of Science and Technology...
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    Crocodile Tears and Forked Tongues: Opposition Unity in Fear, Not Principle

    The arrest of Ranil Wickremasinghe has turned the political stage of Sri Lanka into a theatre of irony and hypocrisy. What is unfolding before our eyes is not a story of loyalty or conviction—it is a spectacle of fear. The sudden “unity” of the opposition is not because they cherish Ranil, but...
  5. I

    Another Mid-air emergency.

    I remember the post. It was answered by a medical professional. Moreover, I coudn't sent you a PM. Stick with one clinician. Do not do doctor shopping. Stop googling for conditions that you imagine. These things you imagine are not real. No need to do any diagnostic tests to verify. Let the...
  6. I

    Another Mid-air emergency.

    An AirAsia flight bound for Bali was forced to circle over Rottnest Island after suffering engine issues shortly after leaving Perth. Flight QZ545 departed Perth for Bali at 6.30pm Sunday but veered off over the Indian Ocean, circling Rottnest Island, and burning fuel so the plane was a safe...
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    MAYDAY: Multiple System Failures on A321.

    Anything that goes up has a finite probability of coming down unexpectedly. Doesn't matter whether it's Boeing, Airbus or another. Between 2013 and 2022, Boeing aircraft were involved in 60 accidents, while Airbus had 50. On the surface, that makes Boeing look worse. But the catch is that...
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    MAYDAY: Multiple System Failures on A321.

    An American Airlines pilot was heard frantically declaring 'mayday' just moments after takeoff in harrowing air traffic control audio. The Philadelphia-bound flight had departed Boston Logan International Airport at 6.45pm on Sunday but was forced to turn around after just 10 minutes as the...
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    🤔❔ 1917 වසරේදී, පෘතුගාලයේ 'Fátima' නගරයේ ජීවත් වූ වැසියන් ආකාසයේ දුටු අද්භූත සංසිද්ධිය කුමක් ද? - "Miracle of the Sun" (Miracle of Fátima) ☀️❓

    One possible explanation is that it's mass hysteria compounded by many staring at the Sun directly causing sort of solar retinopathy. Other places on the Earth nobody saw the sun dancing and even onsite different people had different accounts of what they saw. Another explanation is based on...
  10. I

    RIP Frank Caprio 🙏🏼😢

    RIP..... ☹️
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    සීනි සම්බෝලය ලංකාවට ආවේනිකද?

    They have the sambal chiili. The seeni sambola as we use today could have roots in this during the dutch time but also possible it's our own considering the use of maldive fish.
  12. I

    The Drug That Works TOO Well?

    I had an old thread on ADHD medications. Long term use of Ritalin could have some issues. Depends on your medical condition as well. So make sure that you are being managed by a professional. Briefly all ADHD medications are either stimulants or non-stimulants. Stimulants are the ones used first...
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    The Drug That Works TOO Well?

    An AI generated summary............. Amphetamines: An Overview - Amphetamines are powerful stimulants that can enhance performance in various activities such as work, study, and social interactions. - They have been used historically in various contexts, including military applications and to...
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    දිය ඇලි, කදු වලින් වට උන මන්දාරම් නුවර

    You can drive in any car.... Then should hire a double cab from there to watch the waterfalls. We agreed Rs13,000 for a vehicle, the driver/guide stayed with us from early morning till late evening and took us everywhere. Some climbs are difficult for the ladies and this guy helped them often to...
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    The Drug That Works TOO Well?

  16. I

    Alcohol is amazing....

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    ඉන්ටව් එකේදී මට වුනු වැඩේ

    It's a red flag question... ☹️
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    ඉන්ටව් එකේදී මට වුනු වැඩේ

    I totally agree with you. I can gauge a person by talking with him for a few minutes better than a stupid HR guy. :ROFLMAO:
  19. I

    How to avoid comparing yourself to others?

    Sorry to hear. Most of the people have some sort of problems. One cannot solve all the problems in life, but need to cope up with them. Get away from stupid social media. You don't need to find out how others go on with their lives. Do not judge or measure your appearance, abilities...
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    How to avoid comparing yourself to others?

    Why do you have to compare? This is now refered to as obsessive comparison disorder (also known as constant comparison disorder) ☹️

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