NASA Reproduces a Building Block of Life in Laboratory
11.05.09
Left to right: Stefanie Milam, Michel Nuevo and Scott Sandford.
Photo credit: Dominic Hart/NASA
NASA scientists studying the origin of life have reproduced uracil, a key component of our hereditary material, in the laboratory. They discovered that an ice sample containing pyrimidine exposed to ultraviolet radiation under space-like conditions produces this essential ingredient of life.
Pyrimidine is a ring-shaped molecule made up of carbon and nitrogen and is the basic structure for uracil, part of a genetic code found in ribonucleic acid (RNA). RNA is central to protein synthesis, but has many other roles.
"We have demonstrated for the first time that we can make uracil, a component of RNA, non-biologically in a laboratory under conditions found in space," said Michel Nuevo, research scientist at NASA's Ames Research Center, Moffett Field, Calif. "We are showing that these laboratory processes, which simulate occurrences in outer space, can make a fundamental building block used by living organisms on Earth."
An ice sample is deposited in a chamber, where it is irradiated with high energy UV photons from the hydrogen lamp at approximately - 442 F. The bombarding photons break the chemical bonds in the ice samples, which then form new compounds, such as uracil.
Nuevo is the lead author of a research paper titled “Formation of Uracil from the Ultraviolet Photo-Irradiation of Pyrimidine in Pure Water Ices,” Astrobiology vol. 9 no. 7, published Oct. 1, 2009.
NASA Ames scientists have been simulating the environments found in interstellar space and the outer solar system for years. During this time, they have studied a class of carbon-rich compounds, called polycyclic aromatic hydrocarbons (PAHs), which have been identified in meteorites, and are the most common carbon-rich compound observed in the universe. PAHs typically are six-carbon ringed structures that resemble fused hexagons, or a piece of chicken wire.
http://www.nasa.gov/topics/technology/features/uracil.html
11.05.09
Left to right: Stefanie Milam, Michel Nuevo and Scott Sandford.
Photo credit: Dominic Hart/NASA
NASA scientists studying the origin of life have reproduced uracil, a key component of our hereditary material, in the laboratory. They discovered that an ice sample containing pyrimidine exposed to ultraviolet radiation under space-like conditions produces this essential ingredient of life.
Pyrimidine is a ring-shaped molecule made up of carbon and nitrogen and is the basic structure for uracil, part of a genetic code found in ribonucleic acid (RNA). RNA is central to protein synthesis, but has many other roles.
"We have demonstrated for the first time that we can make uracil, a component of RNA, non-biologically in a laboratory under conditions found in space," said Michel Nuevo, research scientist at NASA's Ames Research Center, Moffett Field, Calif. "We are showing that these laboratory processes, which simulate occurrences in outer space, can make a fundamental building block used by living organisms on Earth."
An ice sample is deposited in a chamber, where it is irradiated with high energy UV photons from the hydrogen lamp at approximately - 442 F. The bombarding photons break the chemical bonds in the ice samples, which then form new compounds, such as uracil.
Nuevo is the lead author of a research paper titled “Formation of Uracil from the Ultraviolet Photo-Irradiation of Pyrimidine in Pure Water Ices,” Astrobiology vol. 9 no. 7, published Oct. 1, 2009.
NASA Ames scientists have been simulating the environments found in interstellar space and the outer solar system for years. During this time, they have studied a class of carbon-rich compounds, called polycyclic aromatic hydrocarbons (PAHs), which have been identified in meteorites, and are the most common carbon-rich compound observed in the universe. PAHs typically are six-carbon ringed structures that resemble fused hexagons, or a piece of chicken wire.
http://www.nasa.gov/topics/technology/features/uracil.html
