Researchers in Canada has come up with a new multi-antibody cocktail that works against Covid-19. When tested with hamsters, it suppressed replication-competent viral titers to undetectable levels in the animals’ lungs.
It's named TATX-03 and studies show that it maintained in vitro neutralizing activity against the B.1.1.7 (alpha), B.1.351 (beta) and P.1 (gamma) variants of concern.
Also further studies showed virus neutralization potency (in vitro) is also not affected by the rapidly spreading Delta variant (B.1.617.2).
One of their scientists stated " “Our TATX-03 cocktail is rationally designed for broad epitope coverage relying on multiple antibodies, which have shown in pre-clinical studies to work synergistically together, to reduce the risk of mutagenic escape, and have the potential to reduce the risk of new variants. We believe this strategy of multi-antibody cocktails is more crucial now with the surge of new variants of concern and breakthrough cases.”
Basically TATX-03 has the potential of being used as a therapy for SARS-CoV-2 infection with resistance to mutagenic escape.
It's named TATX-03 and studies show that it maintained in vitro neutralizing activity against the B.1.1.7 (alpha), B.1.351 (beta) and P.1 (gamma) variants of concern.
Also further studies showed virus neutralization potency (in vitro) is also not affected by the rapidly spreading Delta variant (B.1.617.2).
One of their scientists stated " “Our TATX-03 cocktail is rationally designed for broad epitope coverage relying on multiple antibodies, which have shown in pre-clinical studies to work synergistically together, to reduce the risk of mutagenic escape, and have the potential to reduce the risk of new variants. We believe this strategy of multi-antibody cocktails is more crucial now with the surge of new variants of concern and breakthrough cases.”
Basically TATX-03 has the potential of being used as a therapy for SARS-CoV-2 infection with resistance to mutagenic escape.
