Further to my post in last April on this issue...(copied below)
https://elakiri.com/threads/oxford-vaccine-thrombosis-with-thrombocytopenia-syndrome.1983028/
A just released paper published by a joint team of US & UK scientists led by Alex Baker (Mayo Clinic USA) & Prof Alan Parker (Cardiff University,, UK) sheds more light on the blood clotting issue with the AZ, J&J vaccines.... Possibly Sputnik suffers from the same issue but not officially reported.
The paper state that...
"Vaccines derived from chimpanzee adenovirus Y25 (ChAdOx1), human adenovirus type 26 (HAdV-D26), and human adenovirus type 5 (HAdV-C5) are critical in combatting the severe acute respiratory coronavirus 2 (SARS-CoV-2) pandemic. As part of the largest vaccination campaign in history, ultrarare side effects not seen in phase 3 trials, including thrombosis with thrombocytopenia syndrome (TTS), a rare condition resembling heparin-induced thrombocytopenia (HIT), have been observed. This study demonstrates that all three adenoviruses deployed as vaccination vectors versus SARS-CoV-2 bind to platelet factor 4 (PF4), a protein implicated in the pathogenesis of HIT. We have determined the structure of the ChAdOx1 viral vector and used it in state-of-the-art computational simulations to demonstrate an electrostatic interaction mechanism with PF4, which was confirmed experimentally by surface plasmon resonance. These data confirm that PF4 is capable of forming stable complexes with clinically relevant adenoviruses, an important step in unraveling the mechanisms underlying TTS."
These scientists provide evidence to what the German researchers suggested.... It's the adenovirus interaction with CAR (coxsackie and adenovirus receptor) & PF4 factor that causes the clotting.
Capsid structure of the ChAdOx1 viral vector.
The paper itself is too detailed, but the possible cause of the clotting could be the vector virus getting into the bloodstream. Even though the vaccine is IM, there's a remote possibility of a small quantities of ChAdOx1 enter the blood through minor capillary injuries.....
https://elakiri.com/threads/oxford-vaccine-thrombosis-with-thrombocytopenia-syndrome.1983028/
A just released paper published by a joint team of US & UK scientists led by Alex Baker (Mayo Clinic USA) & Prof Alan Parker (Cardiff University,, UK) sheds more light on the blood clotting issue with the AZ, J&J vaccines.... Possibly Sputnik suffers from the same issue but not officially reported.
The paper state that...
"Vaccines derived from chimpanzee adenovirus Y25 (ChAdOx1), human adenovirus type 26 (HAdV-D26), and human adenovirus type 5 (HAdV-C5) are critical in combatting the severe acute respiratory coronavirus 2 (SARS-CoV-2) pandemic. As part of the largest vaccination campaign in history, ultrarare side effects not seen in phase 3 trials, including thrombosis with thrombocytopenia syndrome (TTS), a rare condition resembling heparin-induced thrombocytopenia (HIT), have been observed. This study demonstrates that all three adenoviruses deployed as vaccination vectors versus SARS-CoV-2 bind to platelet factor 4 (PF4), a protein implicated in the pathogenesis of HIT. We have determined the structure of the ChAdOx1 viral vector and used it in state-of-the-art computational simulations to demonstrate an electrostatic interaction mechanism with PF4, which was confirmed experimentally by surface plasmon resonance. These data confirm that PF4 is capable of forming stable complexes with clinically relevant adenoviruses, an important step in unraveling the mechanisms underlying TTS."
These scientists provide evidence to what the German researchers suggested.... It's the adenovirus interaction with CAR (coxsackie and adenovirus receptor) & PF4 factor that causes the clotting.
Capsid structure of the ChAdOx1 viral vector.
The paper itself is too detailed, but the possible cause of the clotting could be the vector virus getting into the bloodstream. Even though the vaccine is IM, there's a remote possibility of a small quantities of ChAdOx1 enter the blood through minor capillary injuries.....
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