උබල මිග්‍රේන් වලට මොකද කරන්නේ?

kingcharith

Well-known member
  • Aug 18, 2018
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    It's considered as a systemic illness and not just a headache. It's really a brain disorder. There are different subtypes of migraine. For some a simple remedy like cooling the forehead (icepack) while keeping your feet in a warm bath works. Although a long term cure is not available, there are promising new drugs.
    Research has shown that the brain patterns do change 24 hrs ahead of migraine onset. There are a new family of drugs - Calcitonin gene-related peptide (CGRP) which works, but there are side effects including liver damage.
    But later, Monoclonal antobodies (CGRP mAbs) were developed, not cheap but considered safe. Some of these are still awaiting for FDA approval. CGRP mAbs are the latest preventative drugs for migraine. Hopefully may be one day there will be a cure.


    Meka Karana lankawe docala nadda
     

    Lizard Squad

    Well-known member
  • Jul 15, 2015
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    Colombo
    උබල මිග්‍රේන් වලට මොකද කරන්නේ, මන් topirol 25mg & valparine 200මmg ගන්නවා daily 2 years වගෙ එක දිගටම. දවසක් ඩොක්ට කෙනෙක් ලියල දුන්නේ. තාම එක, බෙහෙත් නැවත්තුවොත් ආයිත් එනවා, නැද්ද හොඳ විකල්පයක්,
    Cannabis
     

    MAHESH80

    Well-known member
  • Nov 23, 2018
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    උබල මිග්‍රේන් වලට මොකද කරන්නේ, මන් topirol 25mg & valparine 200මmg ගන්නවා daily 2 years වගෙ එක දිගටම. දවසක් ඩොක්ට කෙනෙක් ලියල දුන්නේ. තාම එක, බෙහෙත් නැවත්තුවොත් ආයිත් එනවා, නැද්ද හොඳ විකල්පයක්,
    මම දැන් දැක්කේ මේ නුල.ඉරුවාරදයට එකම බෙහෙත තියෙන්නේ ලාංකීය ගොබ්බ පුත්තු වෙච්ච අපි ගාව.ඕනේ නම්,pm කරන්න.ගොබ්බයිට සල්ලි වැඩක් නෑ.ලෙඩේ හොදකර ගන්න.(ගොබ්බයො තමයි කුසල් රැස් කරන්නේ)
     

    imhotep

    Well-known member
  • Mar 29, 2017
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    Meka Karana lankawe docala nadda
    CGRP mAbs are not cheap.. Only used in chronic cases. But these are now available in the developed countries.
    There are several of them - erenumab (Aimovig), fremanezumab (Ajovy), galcanezumab (Emgality) & eptinezumab (Vyepti)
    Aimovig, Ajovy and Emgality are taken by an injection with a needle or automatic pen- (like the Diabetes pen)

    Some of these could be available in India. I believe they approved these recently.

    Also in the late stage of development are a family of drugs in tablet form. One of them a nasal spray (zavegepant). But only available in the US still.