එන්නතෙන් අතුරු ආබාධ එන හැටි දැනගනිමු

Thushara buddhika

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  • Aug 30, 2006
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    මු කියන ඒවායේ ඇත්තක් නැතිවාම නෙවෙයි............ අතුරු ආබාධ සැහෙන්න තියෙනවා........
     
  • Apr 15, 2014
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    ප්‍රතිදේහ හැදෙන ප්‍රොසෙස් එකේ වෙනසක් එන්නතෙන් කරන්නෙ නෑ නේද @imhotep ඒකෙන් කරන්නෙ false එලාර්ම් එකක් ට්‍රිගර් කරන එක නේද?

    @පිටියෙ-අප්පු උබව කෝට් කරාට උත්තර දෙන්න ඕනි නෑ මේඑක ඉම්හොටෙප්ට පෙන්නනල අදහස දැනගන්නයි ඕනි.
    ප්‍රතිදේහ හැදෙන ක්‍රියාවලියෙ කිසිම වෙනසක් නෑ. ඒවා ඕනෑවට වඩා හැදෙනවා දීර්ඝකාලීනව. ඔය චන්දිම ජීවන්දරයි නීලිකා මලවිගේයි මාධ්‍ය සාකච්ඡා තිය තිය ඉස්සර පම්පෝරි ගැහුවෙම ඕක නේ.

    ඒක කෙළවගන්න වැඩක් බව උන් දන්නෙ නෑ. ඒ වුණාට ආචාර්‍ය මහාචාරියෝ. 😄

    ඔන්න ඕකයි අවුල.
     

    imhotep

    Well-known member
  • Mar 29, 2017
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    ප්‍රතිදේහ හැදෙන ප්‍රොසෙස් එකේ වෙනසක් එන්නතෙන් කරන්නෙ නෑ නේද @imhotep ඒකෙන් කරන්නෙ false එලාර්ම් එකක් ට්‍රිගර් කරන එක නේද?

    @පිටියෙ-අප්පු උබව කෝට් කරාට උත්තර දෙන්න ඕනි නෑ මේඑක ඉම්හොටෙප්ට පෙන්නනල අදහස දැනගන්නයි ඕනි.
    Yes... That's the answer. In the traditional way, vaccines just imitate an infection. But with mRNA vaccines, the lab created mRNA uses the information in genes to create a blueprint for making proteins. Our cells are a complete manufacturing plant. Given the instructions it can churn out what's desired - in this case the Spike protein gets produced, which our body's defence system recognizes as alien. Whatever the method is the body reacts the same way for the case of infection or vaccination.

    However, I should also say that even though there are many similarities, but also there can be differences between vaccine immunity and natural immunity. Too complex to describe here in full, but the response to an infection or vaccination with a live virus, usually IgM antibodies are made , followed by IgG & others.
    With a mRNA vaccine exposure the B cells are produced and these in turn with the help of T-helper cells that signals the B cells to produce antibodies.
    Note that the second booster shot kicks the T-cells to stimulate the memory B-cells (another type of B cell) to produce large quantity of antibodies.

    Also with mRNA vaccines recent evidence points to the fact that protective antibodies generated can target a broader range of SARS-CoV-2 variants carrying “single letter” changes in a key portion of their spike protein compared to antibodies acquired from an infection.
     
  • Apr 15, 2014
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    Yes... That's the answer. In the traditional way, vaccines just imitate an infection. But with mRNA vaccines, the lab created mRNA uses the information in genes to create a blueprint for making proteins. Our cells are a complete manufacturing plant. Given the instructions it can churn out what's desired - in this case the Spike protein gets produced, which our body's defence system recognizes as alien. Whatever the method is the body reacts the same way for the case of infection or vaccination.

    However, I should also say that even though there are many similarities, but also there can be differences between vaccine immunity and natural immunity. Too complex to describe here in full, but the response to an infection or vaccination with a live virus, usually IgM antibodies are made , followed by IgG & others.
    With a mRNA vaccine exposure the B cells are produced and these in turn with the help of T-helper cells that signals the B cells to produce antibodies.
    Note that the second booster shot kicks the T-cells to stimulate the memory B-cells (another type of B cell) to produce large quantity of antibodies.

    Also with mRNA vaccines recent evidence points to the fact that protective antibodies generated can target a broader range of SARS-CoV-2 variants carrying “single letter” changes in a key portion of their spike protein compared to antibodies acquired from an infection.
    but so called Science got screwed up big really really big this time, 😄

    i predicted this in many of my previous threads many times regarding it. 🤗
     

    හෙළයෙක්

    Well-known member
  • Apr 26, 2014
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    Yes... That's the answer. In the traditional way, vaccines just imitate an infection. But with mRNA vaccines, the lab created mRNA uses the information in genes to create a blueprint for making proteins. Our cells are a complete manufacturing plant. Given the instructions it can churn out what's desired - in this case the Spike protein gets produced, which our body's defence system recognizes as alien. Whatever the method is the body reacts the same way for the case of infection or vaccination.

    However, I should also say that even though there are many similarities, but also there can be differences between vaccine immunity and natural immunity. Too complex to describe here in full, but the response to an infection or vaccination with a live virus, usually IgM antibodies are made , followed by IgG & others.
    With a mRNA vaccine exposure the B cells are produced and these in turn with the help of T-helper cells that signals the B cells to produce antibodies.
    Note that the second booster shot kicks the T-cells to stimulate the memory B-cells (another type of B cell) to produce large quantity of antibodies.

    Also with mRNA vaccines recent evidence points to the fact that protective antibodies generated can target a broader range of SARS-CoV-2 variants carrying “single letter” changes in a key portion of their spike protein compared to antibodies acquired from an infection.
    එල ස්තූතියි පැහැදිලි කිරීමට
     
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    warwickuni

    Well-known member
  • May 21, 2008
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    Yes... That's the answer. In the traditional way, vaccines just imitate an infection. But with mRNA vaccines, the lab created mRNA uses the information in genes to create a blueprint for making proteins. Our cells are a complete manufacturing plant. Given the instructions it can churn out what's desired - in this case the Spike protein gets produced, which our body's defence system recognizes as alien. Whatever the method is the body reacts the same way for the case of infection or vaccination.

    However, I should also say that even though there are many similarities, but also there can be differences between vaccine immunity and natural immunity. Too complex to describe here in full, but the response to an infection or vaccination with a live virus, usually IgM antibodies are made , followed by IgG & others.
    With a mRNA vaccine exposure the B cells are produced and these in turn with the help of T-helper cells that signals the B cells to produce antibodies.
    Note that the second booster shot kicks the T-cells to stimulate the memory B-cells (another type of B cell) to produce large quantity of antibodies.

    Also with mRNA vaccines recent evidence points to the fact that protective antibodies generated can target a broader range of SARS-CoV-2 variants carrying “single letter” changes in a key portion of their spike protein compared to antibodies acquired from an infection.
    Can you please elaborate last paragraph. more and if you can provide a source for part of "too complex to describe here in full," would be thankful. From this pandemic , the importance of Science and investment on that was highlighted. The whole world could not do deal with this pandemic if not for vaccines developed by BioNTec , Moderna, Oxford, etc. We should be thankful for dedication and commitment of these , specially when the world was reducing budget for reserch in Medicine worldwide. I hope this will change with Pandemic and that is the good side of it.
     

    imhotep

    Well-known member
  • Mar 29, 2017
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    The Covid virus has 29,881 nucleotides, this makes it 4^14,941 different possible combinations for its genetic sequence - only counting basic letter changes. However, the Laws governing Protein Folding limits the possible missense mutations in the S-protein, which amounts to a total of 19,440 mutations. So there could be more to come....

    It's not science that's screwed. It was the Chinese who screwed the world - and I said this in Feb 2020. Hope the expert virologists in here who laughed it off will still remember. :(

    Can you please elaborate last paragraph. more and if you can provide a source for part of "too complex to describe here in full," would be thankful. From this pandemic , the importance of Science and investment on that was highlighted. The whole world could not do deal with this pandemic if not for vaccines developed by BioNTec , Moderna, Oxford, etc. We should be thankful for dedication and commitment of these , specially when the world was reducing budget for reserch in Medicine worldwide. I hope this will change with Pandemic and that is the good side of it.
    Used the words "too complex" because you need to refer a textbook on Immunology. Sorry. For what I mentioned in the last para, it was from a NIH funded study published in the Translational Medicine.
    Link: https://pubmed.ncbi.nlm.nih.gov/34103407/

    PS: The mistake was to fund vaccine research only. So everyone jumped on the vaccine bus. Had they initially allocated funds for Drug development, we would have fared better. Yes.. it was the vaccines that offered some level of safety, even it was designed on the Spike protein on the original Wuhan virus. In hindsight that was a mistake, but unforeseen at the time of development.
    ------ Post added on Dec 15, 2021 at 4:24 PM
     
  • Apr 15, 2014
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    Dan na eka nan, pereda newei iye ude gahala, hawasa nati wela tienne
    අනිවා , දියවැඩියා කොලෙස්ටරෝල් ප්‍රෙෂර් වලට වගේ කාලයක් පෙති ගිල ගිල ඉන්න ඇති.

    එහෙම අයට තමයි ඔහොම වෙන්නෙ
     
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    ChoronaSottiya

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  • Sep 13, 2020
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    වදුරව
    ඒ විතරක් නෙවෙයි, ඇට මිදුළු වැය වෙද්දි එතන කුණු ලේ එකතු වෙනවා. එතකොටයි මහන්සිය එන්නේ.
    🤔😄
     
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    scorpion MW

    Well-known member
  • Dec 9, 2014
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    හෙල බිමේ
    දැන් එන්නත ගහපූ උන්ට මෝකකඩ වෙන බලපෑම..
    මේ එන්නත කාලයක් යද්දි power එක අඩු වෙනවා නේද?
     
  • Apr 15, 2014
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    දැන් එන්නත ගහපූ උන්ට මෝකකඩ වෙන බලපෑම..
    තිබ්බ ප්‍රතිශක්තියත් අඩු වෙනවා.
    මේ එන්නත කාලයක් යද්දි power එක අඩු වෙනවා නේද?
    ඔව් ඒක තහවුරු වෙලා තියෙන්නේ
     
    Last edited:

    scorpion MW

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  • Dec 9, 2014
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    හෙල බිමේ
    තිබ්බ ප්‍රතිශක්තියත් අඩු වෙනවා.

    ඔව් ඒක තහවුරු වෙලා තියෙන්නේ
    ඒ උනාට මරණ ගාණ එහෙම අඩු වෙලා තියනවා නෙ බං ?
    3rd dose එක නම් නොගෙන ඉන්න හිතන් ඉන්නේ..
    මගේ යාලුවෙක් ගේ නෑදෑ වෙන prof ල canada වල ඉන්න ඔය vaccine ගහලා නෑ. එයාලා කියලා තියන්නේ sure නෑ කියලා. මගේ යාලුවට ත් ගහන්න එපා කියලා. ඒ උනාට මේකේ ඉන්න බැරි නිසා sinopharm ගහලා
     

    WhyNot1

    Well-known member
  • Nov 27, 2016
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    මම ගොණා සේ 1 සහ 2 ඩෝස් ගැහුවා. වෙලාවට මොකුත් අමාරුවක් නම් ආවෙ නෑ. ඒත් 3 ඩෝස් එක නම් ගහන්නෙ නෑ. එක එක අතුරු ආබාද ආපු දන්න කියන එවුන්ම ඉන්නවා.
     
  • Apr 15, 2014
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    ඒ උනාට මරණ ගාණ එහෙම අඩු වෙලා තියනවා නෙ බං ?
    3rd dose එක නම් නොගෙන ඉන්න හිතන් ඉන්නේ..
    මගේ යාලුවෙක් ගේ නෑදෑ වෙන prof ල canada වල ඉන්න ඔය vaccine ගහලා නෑ. එයාලා කියලා තියන්නේ sure නෑ කියලා. මගේ යාලුවට ත් ගහන්න එපා කියලා. ඒ උනාට මේකේ ඉන්න බැරි නිසා sinopharm ගහලා
    කොරෝනා මරණ අඩු වෙලා තියෙන්නේ vaccine වලින් වෙන මරණ ඒකට එකතු නොකරන නිසා නේ.

    ඒවත් එකතු කෙරුවොත් හැංගෙන්න තැන් නැති වෙනවා. 😄