Agreed, we cant say whether the vaccine is 100% accurate or not at this stage. Because, it is a periodical vaccine . For the people who got vaccinated recently, another round of vaccination is due in March. And what if they show complications afterwards ? Can we reverse an vaccine, which is already injected to our body.
So, it is to early to say whether the vaccine is accurate or not . And there can be complexities, in couple of years time because of the vaccine ? who knows ? what if the initial dosage doesn't make an harm, and if the second does does ?
Am not referring to the immediate response of the immune system. Based on the papers which I read about the vaccine, what they do is they are using part of the virus, in a controlled way to respond our immune system to create responding mechanism towards the virus.
And also I have read that the form of virus is changing from time to time. ( recently we got news about a new form of covid-19, in UK). So, It is obvious that the new formation of the virus could not be controlled by this immediate form of vaccine. They may have to look for another dose of vaccine, to respond to the new formation. and it is going to be an ongoing thing.
Am not an medical expert, but this is what I understood by reading things about this contemporary issue as a normal person.
Anyway, just wondering whether any of these vaccinated people are working with covid-19 infected people without using proper medical protection. If they are 100% confident about the vaccine, they can work with the patients without using protection equipment.
They have to be vaccinated a second time because the vaccine is in two doses. A prime and a booster. The Israeli's are doing the worlds largest vaccine live trial and they are quite satisfied with it.
The only concern with the vaccine are the emerging variants specially the
South African ones. That will require another modified booster and at the moment AZ and BioNTech are working on it. Others will too.
I have copied the vaccine technology from one of my old threads, in case you have missed it. It's written to be understood by anyone.
Don't worry about side effects from the vaccine, what one should really worry are the
after effects of the disease itself. Quite alarming for some of the recovered patients.
<snip>
The Oxford vaccine is an adenovirus vector vaccine. The adenovirus vector used has an
inserted gene that encodes the full-length SARS-CoV-2 spike protein.
The idea to use an adenovirus as a vector to deliver the vaccine is simply because the virus can enter the human cells quite easily by attaching with the host receptors and then release their genome in to the human cells. So this particular vaccine, once inside the human cells will start producing the spike protein, because it's been modified to do so.
The produced spike protein then acts as an antigen to prime the body immune system to recognize SARS-CoV-2 if it infects the body at a later date.
But there's a small snag in the above scenario. There are several adenoviruses that affect us, and many people have adenovirus-specific antibodies that could bind and neutralize these vectors. So, when a person is given a viral-vector vaccine, as well as generating an immune response against the coronavirus’s spike protein, the immune system will also mount a response against the viral vector itself.
Hence the research scientists at Oxford used a clever approach. They used an adenovirus of chimpanzee origin that does not normally infect humans. Hence we would not likely have pre-existing antibodies to the adenovirus vector used. They also changed the adenovirus itself by the deletion of
TWO genes. One of the genes deleted is the one regulating the virus replication - this makes sure that virus cannot create an infection in human cells, and the second deletion was to get the
space to insert the gene that will code for the SARS-CoV-2 spike protein.
OTOH Gamelaya (Russian vaccine developer) used another approach. They used their already existing Ebola vaccine platform. They used used
TWO different human adenovirus vectors – Ad26 and Ad5 (out of the 50 odd that affect humans) – for its two vaccine doses. This hybrid vaccine, with two different vectors for prime and booster vaccinations, is less likely to have one jab generate an immune response against the viral vector that then interferes with the other.
Don't get fooled by the crap on the Internet saying that mRNA or an adenovirus will alter your DNA. Total bull!@#$ and you will not turn into a Chimpanzee.
Our cell machinery does have extended capabilities, that goes beyond manufacturing of human proteins. What happens when we get invaded by a virus? The virus injects it's genetic material, resulting in pieces of mRNA encoding viral proteins being sent to our protein-making machinery. This enables the virus to assemble new viral particles and spread. But that doesn't alter your DNA. Otherwise everytime you fall sick, your DNA will get altered.
It's exactly the same with the vaccine.
As I have mentioned before several adenovirus based vaccines (HIV, Ebola, TB) and several mRNA vaccines (rabies, influenza, cytomegalovirus, and Zika) have been used on humans before. More than 300,000 Zika vaccines has been given in Congo alone.
<snip>
